Isolating biochemical steps resulting in pyroptosis during CAR-T treatment

The biochemical steps resulting in pyroptosis during CAR-T treatment have been isolated by a team of researchers associated with several institutions in China. The group outlines their study of modified immune cells used in the treatment of leukaemia and what they find, in their paper published in the journal Science Immunology.

CAR-T cell therapy is used to treat patients with blood cancers— it includes the removal, genetic mo....