Global monoclonal antibodies market was valued at US$ 123.65 billion in 2020 and is expected to reach US$ 239.01 billion by 2028, growing at a CAGR of 13.1% over the forecast period. Monoclonal antibodies (mAbs) are immunoglobulins that are engineered to target an antigen. At least five monoclonal antibodies per year have been approved by the FDA since 2014 and this trend shows no signs of slowing down. These treatments include a variety of indications such as autoimmune conditions, infectious diseases and oncology. One of the fastest-growing groups of prescription drugs is monoclonal antibodies. When more possible targets are identified with a better understanding the diseases the production of new mAb-based drugs provides new opportunities.
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Over the last decade, cancer immunotherapy, inflammatory disorders, and certain autoimmune diseases are the main fields of research. Monoclonal antibodies embodies the promise of precision medicine which is to produce treatments that are precisely tailored to a particular target because of their exquisite specificity. Regardless of the specific direction that leads to the next wave of monoclonal antibody therapies, therapeutic antibodies can do things that few tiny molecules can do and will remain firmly part of the drug development landscape for years to come.
Monoclonal antibody therapy for a number of conditions has become a vital component of the clinical treatment phase. In order to assess their effectiveness in enhancing survival many mAbs are now being evaluated as adjuvant or first-line therapies. In the future, for the production of therapy using mAbs, knowledge from genome-medical science and genome-informatics for medical care should be important. Currently, monoclonal antibody therapy is gaining more attention. Several monoclonal antibodies are currently being tested, alone and in conjunction with other traditional therapies in clinical trials in phase I and phase II. The monoclonal antibody industry has grown rapidly since the licensing of the first monoclonal antibody for clinical use 30 years ago and is now estimated at billions of dollars.
The most significant factor in the rising demand for therapies would be an increasing elderly population in developed nations over the next 25 years. Cardiovascular disease, cancer, and respiratory diseases are the major causes of death all of which are closely linked to age. Other age-related disorders are significant factors influencing the quality of life such as osteoporosis, arthritis, Alzheimer's, and Parkinson's. Cancer, diabetes, liver and kidney disease mortality has scarcely improved creating big areas for scientific breakthroughs.
This industry includes the manufacturing of monoclonal anti-cancer antibodies to prevent metastasis by reducing cell proliferation, monoclonal immunological antibodies, monoclonal neuropharmacological antibodies, monoclonal anti-infective antibodies (MAbs) and other human and animal MAbs. The biosimilar goal is to reduce the rising cost of healthcare and to deal with economic pressure from the patient and governments to reduce drug prices and improve access to treatment. In recent years, the demand for monoclonal antibodies has undergone several strategic initiatives. Start-ups and mid-sized enterprises are strategically purchased by top businesses in the industry to grow goods and services. Growing number of product launches will aid the Monoclonal Antibodies Market growth over the forecast period. In December 2019, Mylan and Biocon announced the release of a new product in the category of monoclonal antibody therapy. The company launched 'Ogivri,' a trastuzumab-like biosimilar medication. The organization will launch the item for commercial use in the United States. The company's new product will not only produce considerable sales from the monoclonal antibody market, but will also have a tremendous effect on the overall market development in the near future.
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In several fields of medicine and biological science these antibodies are commonly applied. They have started to replace traditional blood banking antibodies and are used in the bacteriology laboratory in the identification of pathogens. In the detection of leukemia and, more recently in the treatment of malignancies monoclonal antibodies are still used. Recent progress in the development of anti-coronavirus mAbs, specifically SARS-CoV and MERS-CoV, may be a possible avenue for prophylaxis or treatment of the novel SARS-CoV-22 coronavirus. It is unlikely that passive immunization of patients with mAbs would result in an outright cure, but it may help to reduce the seriousness of the disease and restrict the replication of the virus. In patients suffering from moderate to serious illness this may be particularly useful and help improve survival rates in these individuals. SARS-CoV and SARS-CoV-2 both join the host cell through the angiotensin-converting enzyme 2 receptor (ACE-2).
The detailed research study provides qualitative and quantitative analysis of monoclonal antibodies market. The market has been analyzed from demand as well as supply side. The demand side analysis covers market revenue across regions and further across all the major countries. The supply side analysis covers the major market players and their regional and global presence and strategies. The geographical analysis done emphasizes on each of the major countries across North America, Europe, Asia Pacific, Middle East & Africa and Latin America.
Key Findings of the Report:
- In application, the cancer segment will lead the market over the forecast period. Increased cancer incidence is expected to increase demand for infusion therapies, contributing to a significant growth in the market for monoclonal antibodies
- North America is projected to become dominant region in the world for monoclonal antibodies. The increasing prevalence of chronic diseases has contributed to an increasing demand for these therapies. The growing number of strategic partnerships and funding for these therapies will also boost the growth of the market in this region.
- Growth in the European market will be driven by the presence of multiple healthcare reimbursement policies. In addition, the increasing prevalence of diseases such as arthritis and inflammatory illnesses will contribute to market growth.
- The major players operating in the market include Amgen Inc., Bristol-Myers Squibb Company, DAIICHI SANKYO COMPANY, LIMITED., Eli Lilly & Co. (acquired ImClone Systems, Inc.), F. Hoffmann-La Roche Ltd, GlaxoSmithKline plc., Johnson & Johnson Services, Inc., Merck & Co., Inc., Novartis AG, Pfizer Inc. and other market participants
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Monoclonal Antibodies Market:
- By Source
- Murine
- Chimeric
- Humanized
- Human
- By Type
- Naked Monoclonal Antibodies
- Conjugated Monoclonal Antibodies
- Bispecific Monoclonal Antibodies
- Others
- By Clinical Trial Phases
- Phase 0
- Phase I
- Phase II
- Phase III
- Phase IV
- By Application
- Diagnostic Testing
- Autoimmune Diseases
- Cancer Treatment
- Breast Cancer
- Stomach Cancer
- Others
- Pregnancy Testing
- Radioimmunodetection (RID) of Cancer
- Radioimmunotheraphy (RIT) of Cancer
- Viral Disease Treatment
- Identifying Pathogens
- Alzheimer’s disease
- Chronic Lymphocytic Leukemia and Non-Hodgkin’s Lymphoma
- Rhesus Disease Immunization
- Systemic Lupus Erythematosus
- Crohn's Disease
- Ulcerative Colitis
- Psoriasis and Rheumatoid Arthritis
- Cardiovascular Disease
- Others
- By End Use
- Hospitals
- Clinics
- Research Institutes
- Others
- By Geography
- North America
- U.S.
- Canada
- Mexico
- Rest of North America
- Europe
- France
- The UK
- Spain
- Germany
- Italy
- Nordic Countries
- Denmark
- Finland
- Iceland
- Sweden
- Norway
- Benelux Union
- Belgium
- The Netherlands
- Luxembourg
- Rest of Europe
- Asia Pacific
- China
- Japan
- India
- New Zealand
- Australia
- South Korea
- Southeast Asia
- Indonesia
- Thailand
- Malaysia
- Singapore
- Rest of Southeast Asia
- Rest of Asia Pacific
- Middle East & Africa
- Saudi Arabia
- UAE
- Egypt
- Kuwait
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Argentina
- Rest of Latin America
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