Microneedles can be used as a pretreatment for skin pore formation. Sharp microneedles penetrate the skin to create holes through which drugs can transport, either for local effect in the skin or for systemic delivery after capillary uptake. The drug can be applied to the skin's surface over the pores with a drug-loaded patch, as is common in traditional transdermal drug delivery. Microneedles are classified into types: solid microneedles for tissue pretreatment, drug-coated microneedles, dissolving microneedles, and hollow microneedles amongst others. The advantage of microneedle arrays is that they reduce patients' anxiety when confronted with a hypodermic needle. The availability of a safer alternative to conventional hypodermic injection is the most important factor driving the growth of microneedle drug delivery systems market. Furthermore, the growing acceptance of safety concerns is fueling the growth of microneedle drug delivery systems market. NanoPass Technologies is in the commercial phase of developing virtually painless intradermal delivery solutions for vaccines and drugs. The company's MicronJet TM microneedle provides an easy-to-use, consistent, and efficient intradermal alternative for practically painless substance delivery. It is compatible with any standard syringe and can be used to inject liquid substances directly into the skin, such as vaccines, drugs, peptides, and dermal fillers.
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During the Covid-19 pandemic, the demand for novel drug delivery systems increased significantly because the virus spreads primarily through respiratory droplets when infected people cough or sneeze. The Richard King Mellon Foundation in new window has awarded a grant to researchers at Carnegie Mellon University College of Engineering and the University of Pittsburgh School of Medicine in new window to create and test a new microneedle array platform capable of delivering vaccines directly into the skin, with the specific goal of improving COVID-19 vaccination in the developing world. Microneedles can be filled with vaccines and delivered painlessly to the skin, where a strong and robust immune response can occur. As a result, the global demand for microneedle drug delivery systems market increased significantly during the pandemic.
Segmental Analysis – Global Microneedle Drug Delivery Systems Market
Based on the type of microneedle drug delivery systems, the solid segment is one of the significant segments in the market. As a pretreatment, solid microneedles are used, after which a topical formulation can diffuse through residual holes in the skin (solid MN). Solid microneedles are mainly made of metal and silicon, which provide strong mechanical properties while being drug-free. Solid microneedles are an array of microscale tapered sharp tips made of a single material that does not contain any drugs or excipients. They are inserted into the skin, creating micron-sized pores on the skin's surface.
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Based on the applications, the drug delivery segment dominated the microneedle drug delivery systems market in 2021. A microneedle device is created by arranging hundreds of microneedles in arrays on a tiny patch to deliver a sufficient amount of drug to produce the desired therapeutic response. It is a novel drug delivery technology that has the potential to provide significant benefits as an alternative to traditional needle injections and other routes of administration.
Among the end-users, the hospital’s segment held a substantial share of the market in 2021 due to the availability of all treatment facilities in hospitals. People in developing economies majorly prefer hospitals for medical treatment. The segment's growth is being fueled by an increase in the number of chronic diseases as well as an increase in the number of hospitals.
Asia Pacific region is the fastest-growing region in the global microneedle drug delivery systems market over the forecast period. The continuous adoption of advanced technologies in the healthcare sector in countries such as India, Japan, and Southeast Asian countries is likely to drive the Asia Pacific region's demand for microneedle drug delivery systems. The market in this region is growing due to an increase in chronic diseases, an increase in government initiatives to raise awareness, growing research activities, and a large population pool. Furthermore, companies anticipate technological advances in microneedle drug delivery systems and develop products accordingly in the market.
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Player Profiles - Global Microneedle Drug Delivery Systems Market:
- 3M Company
- AdminMed / nanoBioSciences LLC
- CosMED Pharmaceutical Co. Ltd.
- ENDODERMA CO., LTD.
- Microdermics Inc.
- Nanopass Tech
- NITTO DENKO CORPORATION
- QUADMEDICINE
- Raphas Co., Ltd.
- SNvia Co. Ltd.
- TheraJect, Inc.
- Trelleborg Group
- VAXXAS
- Zealand Pharma A/S
- Zosano Pharma Corporation
- Other Market Participants
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Global Microneedle Drug Delivery Systems Market:
- By Type
- Solid
- Hollow
- Coated
- Dissolving
- Others
- By Material
- Silicon
- Titanium
- Stainless steel
- Polymers
- Others
- By Application
- Drug Delivery
- Protein
- Water-soluble molecule
- Others
- Vaccine Delivery
- Cancer therapy
- Others
- By End Users
- Hospitals
- Surgical Centers
- Diagnostic Laboratories
- Research Laboratories
- Others
- By Region
- North America (U.S., Canada, Mexico, Rest of North America)
- Europe (France, The UK, Spain, Germany, Italy, Nordic Countries (Denmark, Finland, Iceland, Sweden, Norway), Benelux Union (Belgium, The Netherlands, Luxembourg), Rest of Europe
- Asia Pacific (China, Japan, India, New Zealand, Australia, South Korea, Southeast Asia (Indonesia, Thailand, Malaysia, Singapore, Rest of Southeast Asia), Rest of Asia Pacific
- Middle East & Africa (Saudi Arabia, UAE, Egypt, Kuwait, South Africa, Rest of Middle East & Africa)
- Latin America (Brazil, Argentina, Rest of Latin America)
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